

TTC39B destabilizes retinoblastoma protein promoting hepatic lipogenesis in a sex-specific fashion.
2022
Authors: Hsieh J, Molusky MM
Journal: J Hepatol
2022
Authors: Hsieh J, Molusky MM
Journal: J Hepatol


Loss of the wild-type KRAS allele promotes pancreatic cancer progression through functional activation of YAP1.
2022
Authors: Yan H, Yu CC
Journal: Oncogene
2022
Authors: Yan H, Yu CC
Journal: Oncogene


TAZ-induced Cybb contributes to liver tumor formation in non-alcoholic steatohepatitis.
2022
Authors: Wang X, Zeldin S
Journal: J Hepatol
2022
Authors: Wang X, Zeldin S
Journal: J Hepatol


Addressing dyslipidemic risk beyond LDL-cholesterol.
2022
Authors: Tall AR, Thomas DG
Journal: J Clin Invest
2022
Authors: Tall AR, Thomas DG
Journal: J Clin Invest


Are There Bad ICU Rooms? Temporal Relationship between Patient and ICU Room Microbiome, and Influence on Vancomycin-Resistant EnterococcusColonization.
2022
Authors: Freedberg DE, Richardson M
Journal: mSphere
2022
Authors: Freedberg DE, Richardson M
Journal: mSphere


Estimated Cost-effectiveness of Medical Therapy, Sleeve Gastrectomy, and Gastric Bypass in Patients With Severe Obesity and Type 2 Diabetes.
2022
Authors: Lauren BN, Lim F, Krikhely A
Journal: JAMA Netw Open
2022
Authors: Lauren BN, Lim F, Krikhely A
Journal: JAMA Netw Open


Multiplexed single-cell analysis reveals prognostic and non-prognostic T cell types in human colorectal cancer.
2022
Authors: Masuda K, Kornberg A
Journal: JCI Insight
2022
Authors: Masuda K, Kornberg A
Journal: JCI Insight


A Microsatellite in the Coding Sequence of HLA-A/B Is a Mutation Hotspot in Colon Cancer With Microsatellite Instability.
2022
Authors: Raab WJ, Mazzocchi A, Radice P, Sahoo D, Castelli C, Dalerba P
Journal: Gastroenterology
2022
Authors: Raab WJ, Mazzocchi A, Radice P, Sahoo D, Castelli C, Dalerba P
Journal: Gastroenterology


The gut, its microbiome, and the brain: connections and communications
2021
Authors: Michael D Gershon, Kara Gross Margolis
Journal: J Clin Invest
2021
Authors: Michael D Gershon, Kara Gross Margolis
Journal: J Clin Invest


Adipocyte PHLPP2 inhibition prevents obesity-induced fatty liver
2021
Authors: Utpal Pajvani Lab
Journal: Nat Commun
2021
Authors: Utpal Pajvani Lab
Journal: Nat Commun


Emergence and expansion of SARS-CoV-2 B.1.526 after identification in New York
2021
Authors: Catrin Uhlemann Lab
Journal: Nature
2021
Authors: Catrin Uhlemann Lab
Journal: Nature


Gene-Specific Variation in Colorectal Cancer Surveillance Strategies for Lynch Syndrome
2021
Authors: Fay Kastrinos and Chir Hur Labs
Journal: Gastroenterology
2021
Authors: Fay Kastrinos and Chir Hur Labs
Journal: Gastroenterology


Hepatocyte TLR4 triggers inter-hepatocyte Jagged1/Notch signaling to determine NASH-induced fibrosis
2021
Authors: Utpal Pajvani and Ira Tabas Labs
Journal: Sci Transl Med
2021
Authors: Utpal Pajvani and Ira Tabas Labs
Journal: Sci Transl Med


Interleukin-1β-induced pancreatitis promotes pancreatic ductal adenocarcinoma via B lymphocyte-mediated immune suppression
2021
Authors: Timothy Wang and Ken Olive Labs
Journal: Gut
2021
Authors: Timothy Wang and Ken Olive Labs
Journal: Gut


Maladaptive regeneration – the reawakening of developmental pathways in NASH and fibrosis
2021
Authors: Utpal Pajvani, Ira Tabas, and Robert Schwabe Groups
Journal: Nat Rev Gastroenterol Hepatol
2021
Authors: Utpal Pajvani, Ira Tabas, and Robert Schwabe Groups
Journal: Nat Rev Gastroenterol Hepatol


Mist1+ gastric isthmus stem cells are regulated by Wnt5a and expand in response to injury and inflammation in mice
2021
Authors: Timothy Wang
Journal: Gut
2021
Authors: Timothy Wang
Journal: Gut


Mutant p53 regulates Survivin to foster lung metastasis
2021
Authors: Anil Rustgi, Jianhuan Hu, and dHiroshi Nakagawa Labs
Journal: Genes Dev
2021
Authors: Anil Rustgi, Jianhuan Hu, and dHiroshi Nakagawa Labs
Journal: Genes Dev


Notch activity characterizes a common hepatocellular carcinoma subtype with unique molecular and clinicopathologic features
2021
Authors: Utpal Pajvani and Robert Schwabe Labs
Journal: J Hepatol
2021
Authors: Utpal Pajvani and Robert Schwabe Labs
Journal: J Hepatol


PD-1 Signaling Promotes Tumor-Infiltrating Myeloid-Derived Suppressor Cells and Gastric Tumorigenesis in Mice
2021
Authors: Timothy Wang and Helen Remotti Labs
Journal: Gastroenterology
2021
Authors: Timothy Wang and Helen Remotti Labs
Journal: Gastroenterology


Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations
2021
Authors: Robert Schwabe, Nicholas Arpaia, Helen Remotti, and Peter Sims Labs
Journal: Cancer Cell
2021
Authors: Robert Schwabe, Nicholas Arpaia, Helen Remotti, and Peter Sims Labs
Journal: Cancer Cell


PTHrP Drives Pancreatic Cancer Growth and Metastasis and Reveals a New Therapeutic Vulnerability
2021
Authors: Anil Rustgi Lab
Journal: Cancer Discov
2021
Authors: Anil Rustgi Lab
Journal: Cancer Discov


Robust direct digital-to-biological data storage in living cells
2021
Authors: Harris Wang Lab
Journal: Nat Chem Biol
2021
Authors: Harris Wang Lab
Journal: Nat Chem Biol


Stem cells and origins of cancer in the upper gastrointestinal tract
2021
Authors: Hiroshi Nakagawa, Anil Rustgi, Jianwen Que, and Timothy Wang
Journal: Cell Stem Cell
2021
Authors: Hiroshi Nakagawa, Anil Rustgi, Jianwen Que, and Timothy Wang
Journal: Cell Stem Cell


Systematic dissection of σ70 sequence diversity and function in bacteria
2021
Authors: Harris Wang Lab
Journal: Cell Rep
2021
Authors: Harris Wang Lab
Journal: Cell Rep


The Microbiota-Gut-Brain Axis: From Motility to Mood
2021
Authors: Kara Margolis
Journal: Gastroenterology
2021
Authors: Kara Margolis
Journal: Gastroenterology


Tumor restriction by type I collagen opposes tumor-promoting effects of cancer-associated fibroblasts
2021
Authors: Robert Schwabe, Nicholas Arpaia, Peter Sims, and Ken Olive Labs
Journal: J Clin Invest
2021
Authors: Robert Schwabe, Nicholas Arpaia, Peter Sims, and Ken Olive Labs
Journal: J Clin Invest


Acute Hepatitis Is a Prominent Presentation of the Multisystem Inflammatory Syndrome in Children: A Single-Center Report
2020
Authors: Mercedes Martinez and Kara Margolis Groups
Journal: Hepatology
2020
Authors: Mercedes Martinez and Kara Margolis Groups
Journal: Hepatology


Acute Liver Injury in COVID-19: Prevalence and Association with Clinical Outcomes in a Large U.S. Cohort
2020
Authors: Elizabeth Verna
Journal: Hepatology
2020
Authors: Elizabeth Verna
Journal: Hepatology


BMP Signaling in Development, Stem Cells, and Diseases of the Gastrointestinal Tract
2020
Authors: Jianwen Que
Journal: Annu Rev Physiol
2020
Authors: Jianwen Que
Journal: Annu Rev Physiol


Cholesterol Stabilizes TAZ in Hepatocytes to Promote Experimental Non-alcoholic Steatohepatitis
2020
Authors: Ira Tabas, Utpal Pajvani, and Robert Schwabe Groups
Journal: Cell Metabol
2020
Authors: Ira Tabas, Utpal Pajvani, and Robert Schwabe Groups
Journal: Cell Metabol


Clinical Research in Hepatology in the COVID-19 Pandemic and Post-Pandemic Era: Challenges and the Need for Innovation
2020
Authors: Elizabeth Verna's Group
Journal: Hepatology
2020
Authors: Elizabeth Verna's Group
Journal: Hepatology


Cysteine depletion induces pancreatic tumor ferroptosis in mice
2020
Authors: Kenneth Olive's Group
Journal: Science
2020
Authors: Kenneth Olive's Group
Journal: Science


DAA therapy and long-term hepatic function in advanced/decompensated cirrhosis: Real-world experience from HCV-TARGET cohort
2020
Authors: Elizabeth Verna's Group
Journal: J Hepatol
2020
Authors: Elizabeth Verna's Group
Journal: J Hepatol


Famotidine Use Is Associated With Improved Clinical Outcomes in Hospitalized COVID-19 Patients: A Propensity Score Matched Retrospective Cohort Study
2020
Authors: Daniel Freedberg, Julian Abrams, and Timothy Wang
Journal: Gastroenterology
2020
Authors: Daniel Freedberg, Julian Abrams, and Timothy Wang
Journal: Gastroenterology


Gastrointestinal Symptoms and Coronavirus Disease 2019: A Case-Control Study From the United States
2020
Authors: Daniel Freedberg, Benjamin Lebwohl, and Timothy Wang Groups
Journal: Gastroenterology
2020
Authors: Daniel Freedberg, Benjamin Lebwohl, and Timothy Wang Groups
Journal: Gastroenterology


Gastrointestinal Symptoms as a Major Presentation Component of a Novel Multisystem Inflammatory Syndrome in Children That Is Related to Coronavirus Disease 2019: A Single Center Experience of 44 Cases
2020
Authors: Mercedes Martinez and Kara Margolis Groups
Journal: Gastroenterology
2020
Authors: Mercedes Martinez and Kara Margolis Groups
Journal: Gastroenterology


Gut microbiome in HCC – Mechanisms, diagnosis and therapy
2020
Authors: Robert Schwabe
Journal: J Hepatol
2020
Authors: Robert Schwabe
Journal: J Hepatol


Harmonic Motion Imaging of Pancreatic Tumor Stiffness Indicates Disease State and Treatment Response
2020
Authors: Ken Olive, Yang Han, and Helen Remotti Groups
Journal: Clin Cancer Res
2020
Authors: Ken Olive, Yang Han, and Helen Remotti Groups
Journal: Clin Cancer Res


Hormonal Suppression of Stem Cells Inhibits Symmetric Cell Division and Gastric Tumorigenesis
2020
Authors: Timothy Wang's Group
Journal: Cell Stem Cell
2020
Authors: Timothy Wang's Group
Journal: Cell Stem Cell


Macrophage MerTK Promotes Liver Fibrosis in Nonalcoholic Steatohepatitis
2020
Authors: Ira Tabas, Bill Blaner, and Robert Schwabe Groups
Journal: Cell Metabol
2020
Authors: Ira Tabas, Bill Blaner, and Robert Schwabe Groups
Journal: Cell Metabol


Mechanisms of Fibrosis Development in Nonalcoholic Steatohepatitis
2020
Authors: Robert Schwabe, Ira Tabas, and Utpal Pajvani Groups
Journal: Gastroenterology
2020
Authors: Robert Schwabe, Ira Tabas, and Utpal Pajvani Groups
Journal: Gastroenterology


Mechanobiology of vertebrate gut morphogenesis
2020
Authors: Nandan Nerurkar
Journal: Curr Opin Genet Dev
2020
Authors: Nandan Nerurkar
Journal: Curr Opin Genet Dev


Prox1-positive cells monitor and sustain the murine intestinal epithelial cholinergic niche
2020
Authors: Timothy Wang and Kelley Yan Groups
Journal: Nat Commun
2020
Authors: Timothy Wang and Kelley Yan Groups
Journal: Nat Commun


Recording mobile DNA in the gut microbiota using an Escherichia coli CRISPR-Cas spacer acquisition platform
2020
Authors: Harris Wang and Daniel Freedberg Groups
Journal: Nat Commun
2020
Authors: Harris Wang and Daniel Freedberg Groups
Journal: Nat Commun