Bioimaging Core (BIC)
The Bioimaging Core (BIC) provides state-of-the-art and functional imaging techniques to precisely study mechanisms of health and disease of the digestive tract and liver. Besides a sophisticated suite of state-of-the-art microscopes, the small animal imaging unit will provide different platforms and customized protocols to functionally study signaling and metabolic pathways in all organs of the digested. These analyses are complemented by the development of high resolution MALDI imaging as well of microscopy-resolution SCAPE imaging, a novel near microscopy-resolution optical platform based on endogenous tissue fluorescence in small animals and tissues.
- BIC offers a suite of microscopes for confocal, multiphoton, super-resolution and total internal reflection fluorescence, supported by staff with expertise in digestive-focused microscopy and questions
- BIC offers a small animal imaging unit with magnetic resonance, ultrasound, computed tomography, and optical imaging of mice for functional studies. BIC will work with CU-DLDRC members to develop novel custom in vivo imaging protocols.
- BIC offers the development of project-specific MALDI imaging to detect virtually any small molecule at a near single cell level.
- BIC offers the development of project-specific SCAPE imaging, a novel near microscopy-resolution optical platform based on endogenous tissue fluorescence in small animals and tissues.