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The Columbia University Digestive and Liver Diseases Research Center (CU-DLDRC) promotes collaborative and multidisciplinary research in digestive and liver diseases, integrating expertise in clinical and basic gastroenterology and hepatology with state-of-the-art computational bioinformatics.

We support collaboration among different specialties and backgrounds and promote innovative and creative research approaches. We unite investigators with interests in digestive, liver, and pancreatic physiology and disease in the exploration of creative experimental approaches.
Columbia University
Digestive and Liver Diseases Research Center
&nbsp
 
The Columbia University Digestive and Liver Diseases Research Center (CU-DLDRC) promotes collaborative and multidisciplinary research in digestive and liver diseases, integrating expertise in clinical and basic gastroenterology and hepatology with state-of-the-art computational bioinformatics.

We support collaboration among different specialties and backgrounds and promote innovative and creative research approaches. We unite investigators with interests in digestive, liver, and pancreatic physiology and disease in the exploration of creative experimental approaches.
Columbia University
Digestive and Liver Diseases Research Center
&nbsp
 
The Columbia University Digestive and Liver Diseases Research Center (CU-DLDRC) promotes collaborative and multidisciplinary research in digestive and liver diseases, integrating expertise in clinical and basic gastroenterology and hepatology with state-of-the-art computational bioinformatics.

We support collaboration among different specialties and backgrounds and promote innovative and creative research approaches. We unite investigators with interests in digestive, liver, and pancreatic physiology and disease in the exploration of creative experimental approaches.
Columbia University
Digestive and Liver Diseases Research Center
&nbsp
 
We love digestive research. We enjoy working in teams. We embrace diversity. Together we will achieve more.
Columbia University
Digestive and Liver Diseases Research Center
&nbsp
 
The Columbia University Digestive and Liver Diseases Research Center (CU-DLDRC) promotes collaborative and multidisciplinary research in digestive and liver diseases, integrating expertise in clinical and basic gastroenterology and hepatology with state-of-the-art computational bioinformatics.

We support collaboration among different specialties and backgrounds and promote innovative and creative research approaches. We unite investigators with interests in digestive, liver, and pancreatic physiology and disease in the exploration of creative experimental approaches.
Columbia University
Digestive and Liver Diseases Research Center
&nbsp
 
The Columbia University Digestive and Liver Diseases Research Center (CU-DLDRC) promotes collaborative and multidisciplinary research in digestive and liver diseases, integrating expertise in clinical and basic gastroenterology and hepatology with state-of-the-art computational bioinformatics.

We support collaboration among different specialties and backgrounds and promote innovative and creative research approaches. We unite investigators with interests in digestive, liver, and pancreatic physiology and disease in the exploration of creative experimental approaches.
Columbia University
Digestive and Liver Diseases Research Center

Bioimaging Core (BIC)

The Bioimaging Core (BIC) provides state-of-the-art and functional imaging techniques to precisely study mechanisms of health and disease of the digestive tract and liver. Besides a sophisticated suite of state-of-the-art microscopes, the small animal imaging unit will provide different platforms and customized protocols to functionally study signaling and metabolic pathways in all organs of the digested. These analyses are complemented by the development of high resolution MALDI imaging as well of microscopy-resolution SCAPE imaging, a novel near microscopy-resolution optical platform based on endogenous tissue fluorescence in small animals and tissues.

  • BIC offers a suite of microscopes for confocal, multiphoton, super-resolution and total internal reflection fluorescence, supported by staff with expertise in digestive-focused microscopy and questions
  • BIC offers a small animal imaging unit with magnetic resonance, ultrasound, computed tomography, and optical imaging of mice for functional studies.  BIC will work with CU-DLDRC members to develop novel custom in vivo imaging protocols.
  • BIC offers the development of project-specific MALDI imaging to detect virtually any small molecule at a near single cell level.
  • BIC offers the development of project-specific SCAPE imaging, a novel near microscopy-resolution optical platform based on endogenous tissue fluorescence in small animals and tissues.

The anticipated start date for BIC is March 2022. An update will be provided on this website in December ’21 as well as through a BIC seminar in our seminar series. Once the core starts, a detailed list of services and fee schedule will be provided through this website and the iLab system.

BIC is already working with CU-DLDRC investigators to develop novel digestive focused imaging solutions – if interested, please contact BIC directors Ken Olive and Liza Pon.

Leadership

Kenneth Olive, PhD
Associate Professor
Department of Medicine
Columbia University
Website
Liza Pon, PhD
Professor
Department of Pathology & Cell Biology
Columbia University
Profile