The Bioinformatics and Single Cell Analysis Core (BSCAC) will play a central role in the CU-DLDRC, providing its members with access to GI/liver/pancreatic-focused state-of-the-art bioinformatics analysis and efficient workflows for horizontal integration with other CU-DLDRC cores. The BSCAC will provide analysis of single-cell, single-nucleus, single-organoid RNA-sequencing (RNA-seq), spatial transcriptomics and ATAC-seq for mouse and adult and pediatric human GI/liver/pancreatic samples. Additionally, the BSCAC will offer custom Computational Biology approaches to analyze cell-cell interactions and regulatory processes that mediate disease progression and provide opportunities for diagnostic and/or therapeutic interventions; as well as comprehensive solutions for the analysis of cell- and organoid-based CRISPR/Cas9 and drug screens. Make a Service Request via iLab, please start with a free consultation prior to booking a specific service.